Finite element analysis of knee injury risks in car-to-pedestrian impacts

In vehicle-pedestrian collisions, lower extremities of pedestrians are frequently injured by vehicle front structures. In this study, a finite element (FE) model of THUMS (total human model for safety) was modified in order to assess injuries to a pedestrian lower extremity. Dynamic impact responses of the knee joint of the FE model were validated on the basis of data from the literature. Since in real-world accidents, the vehicle bumper can impact the lower extremities in various situations, the relations between lower extremity injury risk and impact conditions, such as between impact location, angle, and impactor stiffness, were analyzed. The FE simulation demonstrated that the motion of the lower extremity may be classified into a contact effect of the impactor and an inertia effect from a thigh or leg. In the contact phase, the stress of the bone is high in the area contacted by the impactor, which can cause fracture. Thus, in this phase the impactor stiffness affects the fracture risk of bone. In the inertia phase, the behavior of the lower extremity depends on the impact locations and angles, and the knee ligament forces become high according to the lower extremity behavior. The force of the collateral ligament is high compared with other knee ligaments, due to knee valgus motions in vehicle-pedestrian collisions.     

Gene expression profiles in the testis associated with testis-ova in adult Japanese medaka (Oryziaslatipes) exposed to 17α-ethinylestradiol

The occurrence of oocytes in the testis (testis-ova) of several fish species is often associated with exposure of estrogenic chemicals. However, induction mechanisms of the testis-ova remain to be elucidated. To develop marker genes for detecting testis-ova in the testis, adult male medaka were exposed to nominal concentration of 100 ng L⁻¹ of 17α-ethinylestradiol (EE2) for 3-5 weeks, and 800 ng estradiol benzoate (EB) for 3 weeks (experiment I), and a measured concentration of 20 ng L⁻¹ EE2 for 1-6 weeks (experiment II). Histological analysis was performed for the testis, and microarray analyses were performed for the testis, liver and brain. Microarray analysis in the estrogen-exposed medaka liver showed vitellogenin and choriogenin as estrogen responsive genes. Testis-ova were induced in the testis after 4 weeks of exposure to 100 ng L⁻¹ EE2, 3 weeks of exposure to 800 ng EB, and 6 weeks of exposure to 20 ng L⁻¹ EE2. Microarray analysis of estrogen-exposed testes revealed up-regulation of genes related to zona pellucida (ZP) and the oocytes marker gene, 42Sp50. Using quantitative RT-PCR we confirmed that Zpc5 gene can be used as a marker for the detection of testis-ova in male medaka.     

Distribution of Polycyclic Aromatic Hydrocarbons (PAHs) and phenolic endocrine disrupting chemicals in South and Southeast Asian mussels

A comprehensive monitoring survey for polycyclic aromatic hydrocarbons (PAHs) and phenolic endocrine disrupting chemicals (EDCs) utilizing mussels as sentinel organisms was conducted in South and Southeast Asia as a part of the Asian Mussel Watch project. Green mussel (Perna viridis) samples collected from a total of 48 locations in India, Indonesia, Singapore, Malaysia, Thailand, Cambodia, Vietnam, and the Philippines during 1994–1999 were analyzed for PAHs, EDCs including nonylphenol (NP), octylphenol (OP) and bisphenol A (BPA), and linear alkylbenzenes (LABs) as molecular markers for sewage. Concentrations of NP ranged from 18 to 643 ng/g-dry tissue. The highest levels of NP in Malaysia, Singapore, the Philippines, and Indonesia were comparable to those observed in Tokyo Bay. Elevated concentrations of EDCs were not observed in Vietnam and Cambodia, probably due to the lower extent of industrialization in these regions. No consistent relationship between concentrations of phenolic EDCs and LABs were found, suggesting that sewage is not a major source of EDCs. Concentrations of PAHs ranged from 11 to 1,133 ng/g-dry, which were categorized as “low to moderate” levels of pollution. The ratio of methylphenanthrenes to phenanthrene (MP/P ratio) was >1.0 in 20 out of 25 locations, indicating extensive input of petrogenic PAHs. This study provides a bench-mark for data on the distribution of anthropogenic contaminants in this region, which is essential in evaluating temporal and spatial variation and effect of future regulatory measures.     

Equity rules for burden sharing in the mitigation process of climate change

Although international negotiation on the mitigation of climate change is a process of determining burden-sharing rules between countries, there has been no clear agreement on equity principles for burden sharing. During the negotiating process up to the Kyoto Protocol, various proposals were made on such burden-sharing rules, but an agreement on emission targets for Annex I countries was achieved without explicitly agree-ing to any rules. In the next phase of the negotiation, debates on emission targets are likely to shift from those between developed countries to those between all parties to the convention. In such a phase, debates on burden-sharing rules will be revisited. The purpose of this paper is: (1) to determine implicitly a formula for the rule for burden sharing between Annex I countries that was considered to be underlying the emission targets of the Kyoto Protocol, and (2) to examine plausible emission targets and timing of commitments for non-Annex I countries in the future by using the result of the analysis on the Kyoto Protocol. A multi-regression method is used for this purpose. It was concluded that the burden sharing between Annex I countries in the Kyoto Protocol can mostly be explained by three variables: the increase in the rate of CO₂ emission during the years 1990 to 2010, the increase in the rate of afforestation between 1990 and 1995, and the GDP per capita at the time of negotiation. The timing of future commitments of developing countries and the levels of targets differ widely, depending on which index or formula is agreed as “equitable”. Some of the developing countries would have to start limiting their emissions within several years if GDP per capita or CO₂ per capita were chosen as the burden-sharing indicator. Developing countries would not have to make commitments until the mid-late 21st century if population growth rate were chosen. If the inferred formula of the Kyoto Protocol were applied to developing countries, they would have had to start mild limitation from 1990.     

Effective diffusivity of the uranyl ion in a granite from Inada, Ibaraki, Japan

The effective diffusivity of uranium(VI) in Inada granite has been determined by through-diffusion. Experiments were performed at room temperature (20–25°C) in a 0.1 mol 1⁻¹ KCl solution where uranium is present predominantly as the poorly sorbing UO₂²⁺. An effective diffusivity (D_e) of (3.6 ± 1.6) × 10⁻¹⁴ m² s⁻¹ was obtained, close to that for uranine (nonsorbing organic tracer), but one order of magnitude lower than those obtained for Sr²⁺ and NpO₂⁺, and two orders of magnitude lower than that obtained for I⁻. According to well established theory, a proportional relationship exists between D_e and the diffusivity in the bulk of the solution (D_v). The effective diffusivity obtained in granite was not proportional to D_v. This agrees with results obtained for effective diffusivity in a Swedish granite. The ratio D_e/D_v was found to be not constant but increased with D_e or D_v. This result suggests a limit to the application of the theory.     

RUNOFF VOLUME ESTIMATION USING GIS TECHNIQUES1

ABSTRACT: Rainfall runoff of six watersheds was modeled via the Soil Conservation Service runoff curve number model in two ways: conventionally (manually) and via a geographic information system (GIS). Input data (elevation, soils, and landcover) were digital for the latter method. In contrast to previous studies, the GIS was ised for all phases of the modeling process, including watershed delineation and routing of runoff. A comparison between the two methods was consistent with results reported by others and indicates that the use of a GIS is an acceptable alternative to the conventional method for watersheds lacking relatively flat terrain. Given this limitation, the GIS method may prove advantageous over manual methods when study areas are large or numerous, runoff is modeled repetitively, alternative landcover scenarios are explored, or a digital database already exists for the study area.